Organic Chemistry I: Structure and Reactivity

The lecture portion of this course will be taught using “flipped class” pedagogy. Students will watch videos prior to class, and classroom time will be dedicated to small group problem solving with faculty guidance. The course will provide students with an introduction to the structure and reactivity of organic molecules sufficient to continue directly to the study of biochemistry (CHEM 0322). Topics covered will include models of chemical bonding, acid-base relationships, three-dimensional molecular structure (conformations and stereochemistry), reaction mechanisms and energy diagrams, substitution and elimination reactions, carbonyl reactions (additions, reductions, interconversions, and alpha-reactivity), and the fundamentals of biological molecules (carbohydrates, DNA, and RNA). Laboratory experiments will relate to purification techniques (recrystallization, distillation, extraction, and chromatography), as well as microscale organic reactions that complement the lecture material. (CHEM 0104 or CHEM 0107) 3 hrs. lect., 3 hrs. lab.