Exercise Biochemistry and the Limits of Human Endurance

In this course we will investigate the biochemical, biological, genetic, and psychological factors associated with athletic performance. We will begin by discussing the origins of exercise physiology in the early 1900’s, introducing topics such as metabolic fuels and their utilization, oxygen and water, metabolism, and physiological adaptations to training. Special attention will be paid to muscle (power) and pulmonary organization and function (VO2 max), and how psychology and the brain (the master regulator) contribute to achieve maximum performance. We will bring these topics to the present by reading and discussing papers from the popular and primary literature. Films and guest lectures by experts will provide a personal perspective. The seminar will conclude by considering controversies such as performance enhancing drugs and sex determination.